2,2,2-Trichloroethanol

2,2,2-Trichloroethanol
Names
IUPAC name
2,2,2-Trichloroethanol
Identifiers
115-20-8 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:28094 YesY
ChEMBL ChEMBL1171 YesY
ChemSpider 7961 YesY
ECHA InfoCard 100.003.701
2293
KEGG C07490 YesY
UNII AW835AJ62N YesY
Properties
C2H3Cl3O
Molar mass 149.40 g/mol
Density 1.55 g/cm3
Melting point 17.8 °C (64.0 °F; 290.9 K)
Boiling point 151 °C (304 °F; 424 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

2,2,2-Trichloroethanol is an organic compound related to ethanol, except the hydrogen atoms at position 2 are replaced with chlorine atoms. In humans, its pharmacological effects are similar to those of its prodrugs, chloral hydrate and chlorobutanol. It has, historically, been used as a sedative hypnotic.[1] The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.[2]

See also

References

  1. ↑ The Merck Index, 13th Edition.
  2. ↑ S. Budavari; M. O'Neil; Ann Smith; P. Heckelman; J. Obenchain (15 March 1996). The Merck Index (12th print ed.). Taylor & Francis. ISBN 978-0-911910-12-4.



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