Caricain
| Caricain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.22.30 | ||||||||
| CAS number | 39307-22-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Caricain (EC 3.4.22.30, papaya peptidase A, papaya peptidase II, papaya proteinase, papaya proteinase III, papaya proteinase 3, proteinase omega, papaya proteinase A, chymopapain S, Pp) is an enzyme.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- Hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain
This enzyme is isolated from papaya plant, Carica papaya.
References
- ↑ Schack, P. (1967). "Fractionation of proteolytic enzymes of dried papaya latex. Isolation and preliminary characterization of a new proteolytic enzyme". C. R. Trav. Carlesberg. 36: 67–83. PMID 6043136.
- ↑ Robinson, G.W. (1975). "Isolation and characterization of papaya peptidase A from commercial chymopapain". Biochemistry. 16: 3695–3700. doi:10.1021/bi00687a028. PMID 240390.
- ↑ Polgár, L. (1984). "Problems of classification of papaya latex proteinases". Biochem. J. 221: 555–556. PMID 6383350.
- ↑ Brocklehurst, K.; Salih, E.; McKee, R.; Smith, H. (1985). "Fresh non-fruit latex of Carica papaya contains papain, multiple forms of chymopapain A and papaya proteinase". Biochem. J. 228: 525–527. PMID 4015629.
- ↑ Zucker, S.; Buttle, D.J.; Nicklin, M.J.H.; Barrett, A.J. (1985). "Proteolytic activities of papain, chymopapain and papaya proteinase III". Biochim. Biophys. Acta. 828: 196–204. doi:10.1016/0167-4838(85)90057-3. PMID 3919769.
- ↑ Dubois, T.; Kleinschmidt, T.; Schnek, A.G.; Looze, Y.; Braunitzer, G. (1988). "The thiol proteinases from the latex of Carica papaya L. II. The primary structure of proteinase". Biol. Chem. Hoppe-Seyler. 369: 741–754. doi:10.1515/bchm3.1988.369.2.741. PMID 3063283.
External links
- Caricain at the US National Library of Medicine Medical Subject Headings (MeSH)
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