Photosensitizer

A photosensitizer being used in photodynamic therapy.

A photosensitizer is a molecule that produces a chemical change in another molecule in a photochemical process.[1] Photosensitizers are commonly used in polymer chemistry in reactions such as photopolymerization, photocrosslinking, and photodegradation.[2] Photosensitizers generally act by absorbing ultraviolet or visible region of electromagnetic radiation and transferring it to adjacent molecules. Photosensitizers usually have large de-located π systems, which lower the energy of HOMO orbitals and its absorption of light might be able to ionize the molecule.

Chlorophyll act as a photosensitizer in photosynthesis of carbohydrates in plants:

6CO2 + 6H2O → C6H12O6 + 6O2

Applications

Medical

Photosensitisers are a key part of Photodynamic therapy (PDT) which is used to treat some cancers. They help to produce singlet oxygen to damage tumours. They can be divided into porphyrins, chlorophylls and dyes - See Photodynamic_therapy#Photosensitizers

See also

References

  1. ↑ "Photosensitization". 2009. doi:10.1351/goldbook.P04652.
  2. ↑ Alger, Mark (1996). Polymer science dictionary (2nd ed.). London: Chapman & Hall. ISBN 0412608707.

External links

Look up photosensitizer in Wiktionary, the free dictionary.


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