Morbillivirus
Morbillivirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae. Humans, dogs, cats, cattle, and cetaceans serve as natural hosts. This genus currently included seven species. Diseases associated with viruses classified in this genus include: measles: fever, rash; animal: acute febrile respiratory tract infection.[1][2]
Taxonomy
Table legend: "*" denotes type species.
Structure
Morbillivirions are enveloped, with spherical geometries. The diameter is around 150 nm. Genomes are linear, around 15-16kb in length. The genome codes for 8 proteins.[1]
Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
Morbillivirus | Spherical | | Enveloped | Linear | Monopartite |
Life Cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaching to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering, through co-transcriptional RNA editing is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by budding.
Human, dog, cattle, and cetacean serve as the natural host. Transmission routes are respiratory.[1]
Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
Morbillivirus | Humans; dogs; cats; cetaceans | None | Glycoprotein | Budding | Cytoplasm | Cytoplasm | Aerosols |
References
External links