Menometrorrhagia

Menometrorrhagia
Classification and external resources
ICD-10 N92.1
ICD-9-CM 626.2

Menometrorrhagia is a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal. It is thus a combination of metrorrhagia and menorrhagia.

Epidemiology

It occurs in up to 24% of women ages 40-55 years.[1]

Causes

It can occur due to any of several causes, including hormonal imbalance, endometriosis, uterine fibroids, usage of progestin-only contraception, or cancer.[2] It can lead to anemia in long-standing cases.

Workup

The initial workup includes exclusion of pregnancy and cancer, by performing a pregnancy test, a pelvic exam and a gynecologic ultrasound. Further workup depends on outcomes of the preceding tests and may include hydrosonography, hysteroscopy, endometrial biopsy, and magnetic resonance imaging.[1]

Treatment

Treatment depends on the cause. In cases where malignancy is ruled out, hormone supplementation or the therapeutic use of hormonal contraception is usually recommended to induce bleeding on a regular schedule. Selective progesterone receptor modulators (SPRMs) are sometimes used to stop uterine bleeding.[2]

References

  1. 1 2 Donnez, J. (2011). "Menometrorrhagia during the premenopause: An overview". Gynecological Endocrinology. 27: 1114–1119. doi:10.3109/09513590.2012.637341. PMID 22182054.
  2. 1 2 Bouchard, Philippe (December 2011). "Current and future medical treatments for menometrorrhagia during the premenopause". Gynecological Endocrinology. 27 (Supplement 1): 1120–1125. doi:10.3109/09513590.2012.638754. ISSN 0951-3590. PMID 22182055.
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