Congenital hemolytic anemia

Congenital hemolytic anemia
Classification and external resources
Specialty	hematology
ICD-10	D55-D58
ICD-9-CM	282
MeSH	D000745

Congenital hemolytic anemia (or hereditary hemolytic anemia) refers to hemolytic anemia which is primarily due to congenital disorders.^[1]

Types

Basically classified by causative mechanism, types of congenital hemolytic anemia include:

Genetic conditions of RBC Membrane
- Hereditary spherocytosis
- Hereditary elliptocytosis
Genetic conditions of RBC metabolism (enzyme defects). This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abdormalities as well, but rather encompassing defects of glycolysis in the erythrocyte.^[2]
- Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism)
- Pyruvate kinase deficiency
- Aldolase A deficiency
Hemoglobinopathies^[3]/genetic conditions of hemoglobin

↑ Rahman SA, Jamal CY (June 2002). "Congenital hemolytic anemia in Bangladesh: types and clinical manifestations". Indian Pediatr. 39 (6): 574–7. PMID 12084953.
↑ medconditions.net > Hemolytic Congenital, Nonspherocytic Anemia Definition Retrieved April 15, 2011
↑ Shah A (November 2004). "Hemoglobinopathies and other congenital hemolytic anemia". Indian J Med Sci. 58 (11): 490–3. PMID 15567909.

↑

Polycythemia	Polycythemia vera

↓

Hereditary	enzymopathy: G6PD glycolysis PK TI HK hemoglobinopathy: Thalassemia alpha beta delta Sickle-cell disease/trait HPFH membrane: Hereditary spherocytosis Minkowski–Chauffard syndrome Hereditary elliptocytosis Southeast Asian ovalocytosis Hereditary stomatocytosis

Acquired	Autoimmune WAHA CAD PCH membrane PNH MAHA TM HUS Drug-induced autoimmune Drug-induced nonautoimmune Hemolytic disease of the newborn

Other

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