Bacillolysin
| Bacillolysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.24.28 | ||||||||
| CAS number | 9080-56-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Bacillolysin (EC 3.4.24.28, Bacillus metalloendopeptidase, Bacillus subtilis neutral proteinase, anilozyme P 10, Bacillus metalloproteinase, Bacillus neutral proteinase, megateriopeptidase) is an enzyme.[1][2][3][4][5][6][7][8][9][10] This enzyme catalyses the following chemical reaction
- Similar, but not identical, to that of thermolysin
This enzyme is present in many Bacillus species, including B. subtilis, B. amyloliquefaciens, B. megaterium, B. mesentericus, B. cereus and B. stearothermophilus.
References
- ↑ Morihara, K.; Tsuzuki, H.; Oka, T. (1968). "Comparison of the specificities of various neutral proteinases from microorganisms". Arch. Biochem. Biophys. 123: 572–588. doi:10.1016/0003-9861(68)90179-3. PMID 4967801.
- ↑ Millet, J.; Acher, R. (1969). "Spécificité de la mégatériopeptidase: une amino-endopeptidase à caractère hydrophobe". Eur. J. Biochem. 9: 456–462. doi:10.1111/j.1432-1033.1969.tb00631.x. PMID 4980359.
- ↑ Feder, J.; Keay, L.; Garrett, L.R.; Cirulis, N.; Moseley, M.H.; Wildi, B.S. (1971). "Bacillus cereus neutral protease". Biochim. Biophys. Acta. 251: 74–78. doi:10.1016/0005-2795(71)90061-4. PMID 5002444.
- ↑ Holmquist, B.; Vallee, B.L. (1976). "Esterase activity of zinc neutral proteases". Biochemistry. 15: 101–107. doi:10.1021/bi00646a016. PMID 2276.
- ↑ Vasantha, N.; Thompson, L.D.; Rhodes, C.; Banner, C.; Nagle, J.; Filpula, D. (1984). "Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein". J. Bacteriol. 159: 811–819. PMID 6090391.
- ↑ Yang, M.Y.; Ferrari, E.; Henner, D.J. (1984). "Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation". J. Bacteriol. 160: 15–21. PMID 6090407.
- ↑ Takagi, M.; Imanaka, T.; Aiba, S. (1985). "Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus". J. Bacteriol. 163: 824–831. PMID 2993245.
- ↑ Sidler, W.; Niederer, E.; Suter, F.; Zuber, H. (1986). "The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase". Biol. Chem. Hoppe-Seyler. 367: 643–657. doi:10.1515/bchm3.1986.367.2.643. PMID 3092843.
- ↑ Pauptit, R.A.; Karlson, R.; Picot, D.; Jenkins, J.A.; Niklaus-Reimer, A.-S.; Jansonius, J.N. (1988). "Crystal structure of neutral protease from Bacillus cereus refined at 3.0 Å resolution and comparison with the homologous but more thermostable enzyme thermolysin". J. Mol. Biol. 199: 525–537. doi:10.1016/0022-2836(88)90623-7. PMID 3127592.
- ↑ Stoeva, S.; Kleinschmidt, T.; Mesrob, B.; Braunitzer, G. (1990). "Primary structure of a zinc protease from Bacillus mesentericus strain 76". Biochemistry. 29: 527–534. doi:10.1021/bi00454a029. PMID 2302386.
External links
- Bacillolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
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