1,2-Dimethylhydrazine
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| Names | |
|---|---|
| IUPAC name
1,2-Dimethylhydrazine[1] | |
| Other names | |
| Identifiers | |
540-73-8  | |
| 3D model (Jmol) | Interactive image |
| Abbreviations | SDMH[2] |
| ChEBI | CHEBI:73755  |
| ChEMBL | ChEMBL162921 |
| ChemSpider | 1282 |
| ECHA InfoCard | 100.149.162 |
| KEGG | C19176 |
| MeSH | 1,2-Dimethylhydrazine |
| PubChem | 1322 |
| UNII | IX068S9745 |
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| Properties[3] | |
| C2H8N2 | |
| Molar mass | 60.10 g·mol−1 |
| Appearance | Colourless liquid |
| Odor | Ichtyal, ammoniacal |
| Density | 827.4 kg m−3 (at 20 °C) |
| Melting point | −9 °C (16 °F; 264 K) |
| Boiling point | 87 °C; 188 °F; 360 K |
| Miscible | |
| Thermochemistry | |
| 171.04 J K−1 mol−1 | |
| Std molar entropy (S |
199.15 J K−1 mol−1 |
| Std enthalpy of combustion (ΔcH |
−1987–−1978 kJ mol−1 |
| Related compounds | |
| Related compounds |
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| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
1,2-Dimethylhydrazine, or symmetrical dimethylhydrazine, is one of the three isomers of dimethylhydrazine. It is a potent carcinogen that acts as a DNA methylating agent. It is used to induce colon tumors in experimental animals - particularly mice and feline cell samples.[1][4][5]
See also
References
- 1 2 1,2-Dimethylhydrazine from PubChem
- 1 2 3 4 74-79-3 1,2-Dimethylhydrazine
- ↑ Record of 1,2-Dimethylhydrazin in the GESTIS Substance Database of the IFA, accessed on 21 March 2008
- ↑ Cruse, J. P.; Lewin, M. R.; Ferulano, G. P.; Clark, C. G. (1978). "Co-carcinogenic effects of dietary cholesterol in experimental colon cancer". Nature. 276 (5690): 822–5. doi:10.1038/276822a0. PMID 723955.
- ↑ Wijnands, M.V.W. (1999). "A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds". Carcinogenesis. 20 (4): 651–6. doi:10.1093/carcin/20.4.651. PMID 10223195.
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