Urethanase
urethanase | |||||||||
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Identifiers | |||||||||
EC number | 3.5.1.75 | ||||||||
CAS number | 122007-70-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, an urethanase (EC 3.5.1.75) is an enzyme that catalyzes the chemical reaction
- urethane + H2O ethanol + CO2 + NH3
Thus, the two substrates of this enzyme are urethane and H2O, whereas its 3 products are ethanol, CO2, and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is urethane amidohydrolase (decarboxylating). This enzyme is also called urethane hydrolase.
References
- Kobashi K, Takebe S, Sakai T. "Urethane-hydrolyzing enzyme from Citrobacter sp". Chem. Pharm. Tokyo. Bull. (5): 1326–8. PMID 2393957.
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