UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase
Identifiers
EC number 3.6.1.57
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase (EC 3.6.1.57, PseG, UDP-6-deoxy-AltdiNAc hydrolase, Cj1312) is an enzyme with systematic name UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose hydrolase.[1][2] This enzyme catalyses the following chemical reaction

UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + H2O 2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + UDP

The enzyme is involved in biosynthesis of pseudaminic acid.

References

  1. Liu, F.; Tanner, M.E. (2006). "PseG of pseudaminic acid biosynthesis: a UDP-sugar hydrolase as a masked glycosyltransferase". J. Biol. Chem. 281: 20902–20909. doi:10.1074/jbc.m602972200. PMID 16728396.
  2. Schoenhofen, I.C.; McNally, D.J.; Brisson, J.R.; Logan, S.M. (2006). "Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction". Glycobiology. 16: 8C–14C. doi:10.1093/glycob/cwl010. PMID 16751642.
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