Type II site-specific deoxyribonuclease

Identifiers

Databases

PDB structures

Type II site-specific deoxyribonuclease (EC 3.1.21.4, type II restriction enzyme) is an enzyme.^[1] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates

References

↑ Roberts, R.J. (1990). "Restriction enzymes and their isoschizomers". Nucleic Acids Res. 18: 2331–2365. doi:10.1093/nar/18.suppl.2331. PMID 2159140.

3.1.1: Carboxylic
ester hydrolases

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease

Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex

either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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