Trimethylthiazoline
 | |
| Names | |
|---|---|
| IUPAC name
2,4,5-Trimethyl-4,5-dihydro-1,3-thiazole | |
| Identifiers | |
| 3D model (Jmol) | Interactive image |
| PubChem | 263626 |
| |
| |
| Properties | |
| C6H11NS | |
| Molar mass | 129.22 g·mol−1 |
| Appearance | Light yellow liquid |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 (what is  ?) | |
| Infobox references | |
Trimethylthiazoline (TMT or 2,5-dihydro-2,4,5-trimethylthiazoline) is a constituent of fox urine that is an innately aversive odor to rodents. The chemical is liquid at room temperature and has a very light yellow color which darkens on oxygen exposure over time.
Research
Researchers at SRQBio were able to synthesize TMT and use it with a combination of other stressors such as foot shocks/loud noises as a natural predator psychogenic stress to study posttraumatic stress disorder in rodents.[1] TMT has been called an "innate threat stimulus" because of how it "induces a number of fear and defensive behaviors" in naive mice and rats.[2]
References
- ↑ "Trimethylthiazoline (TMT - a component of fox feces/urine)".
- ↑ Goswami, S; Rodríguez-Sierra, O (2013). "Animal models of post-traumatic stress disorder: face validity". Frontiers in Neuroscience. doi:10.3389/fnins.2013.00089.
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