Translocase

Translocase is a general term for a protein that assists in moving another molecule, usually across a membrane. Translocases are the most common secretion system in Gram positive bacteria.

It is also a historical term for the protein now called elongation factor G, due to its function in moving the tRNA and mRNA through the ribosome.

Examples

ornithine translocase (SLC25A15), associated with ornithine translocase deficiency.
carnitine-acylcarnitine translocase (SLC25A20), associated with carnitine-acylcarnitine translocase deficiency.
Translocase of outer mitochondrial membrane 40 (TOMM40), a protein encoded by the TOMM40 gene, whose alleles differentially impact the risk for Alzheimer's disease

This article is issued from Wikipedia - version of the 10/4/2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.