TRIM15

TRIM15
Identifiers
Aliases	TRIM15, RNF93, ZNF178, ZNFB7, tripartite motif containing 15
External IDs	MGI: 1916347 HomoloGene: 23819 GeneCards: TRIM15
Gene ontology Molecular function • zinc ion binding • protein binding • metal ion binding Cellular component • intracellular Biological process • negative regulation of viral release from host cell • negative regulation of intracellular transport of viral material • mesodermal cell fate determination • positive regulation of sequence-specific DNA binding transcription factor activity • innate immune response • positive regulation of RIG-I signaling pathway • positive regulation of NF-kappaB transcription factor activity • positive regulation of type I interferon production Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	89870	69097
Ensembl	n/a	ENSMUSG00000050747
UniProt	Q9C019	n/a
RefSeq (mRNA)	NM_033229 NM_052812	NM_001024134 NM_001177872
RefSeq (protein)	NP_150232.2	n/a
Location (UCSC)	Chr 6: 30.16 – 30.17 Mb	Chr 17: 36.86 – 36.87 Mb
PubMed search	[1]	[2]
Wikidata

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.^[3][4][5][6]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.^[6]

References

Further reading