T-cell vaccine

For vaccination with T cells, see T-cell vaccination.

A T-cell vaccine is a vaccine designed to induce protective T-cells.[1]

T-cell vaccines are designed to induce cellular immunity. They are also referred to as cell-mediated immune (CMI) vaccines.[2]

It is thought that they can be more effective than conventional [B-cell] vaccines for protection from microbes that hide inside host cells, and viruses (such as HIV or influenza) that mutate rapidly.

T-cell vaccines underwent clinical trials for HIV/AIDS.[3]

As of July 2012 none have been approved.[4]

References

  1. ↑ "T cell vaccines for microbial infections". 2005.
  2. ↑ Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
  3. ↑ "T-Cell Vaccine Strategies for Human Immunodeficiency Virus, the Virus with a Thousand Faces". 2009.
  4. ↑ "T-cell Vaccines Could Treat Elusive Diseases".


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