Streptomycin-6-phosphatase
| streptomycin-6-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.39 | ||||||||
| CAS number | 9055-33-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a streptomycin-6-phosphatase (EC 3.1.3.39) is an enzyme that catalyzes the chemical reaction
- streptomycin 6-phosphate + H2O streptomycin + phosphate
Thus, the two substrates of this enzyme are streptomycin 6-phosphate and H2O, whereas its two products are streptomycin and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is streptomycin-6-phosphate phosphohydrolase. Other names in common use include streptomycin 6-phosphate phosphatase, streptomycin 6-phosphate phosphohydrolase, and streptomycin-6-P phosphohydrolase. This enzyme participates in streptomycin biosynthesis.
References
- Walker JB, Skorvaga M (1973). "Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine". J. Biol. Chem. 248 (7): 2441–6. PMID 4121457.
- Walker MS, Walker JB (1971). "Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate". J. Biol. Chem. 246 (22): 7034–40. PMID 4331203.
This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.