Stemar-13-ene synthase

Stemar-13-ene synthase
Identifiers
EC number 4.2.3.33
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Stemar-13-ene synthase (EC 4.2.3.33, OsDTC2, OsK8, OsKL8, OsKS8, stemarene synthase, syn-stemar-13-ene synthase) is an enzyme with systematic name 9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming).[1][2] This enzyme catalyses the following chemical reaction

9alpha-copalyl diphosphate stemar-13-ene + diphosphate

This diterpene cyclase produces stemar-13-ene, a putative precursor of the rice phytoalexin oryzalexin S.

References

  1. Mohan, R.S.; Yee, N.K.; Coates, R.M.; Ren, Y.Y.; Stamenkovic, P.; Mendez, I.; West, C.A. (1996). "Biosynthesis of cyclic diterpene hydrocarbons in rice cell suspensions: conversion of 9,10-syn-labda-8(17),13-dienyl diphosphate to 9β-pimara-7,15-diene and stemar-13-ene". Arch. Biochem. Biophys. 330: 33–47. doi:10.1006/abbi.1996.0223. PMID 8651702.
  2. Nemoto, T.; Cho, E.M.; Okada, A.; Okada, K.; Otomo, K.; Kanno, Y.; Toyomasu, T.; Mitsuhashi, W.; Sassa, T.; Minami, E.; Shibuya, N.; Nishiyama, M.; Nojiri, H.; Yamane, H. (2004). "Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice". FEBS Lett. 571 (1-3): 182–186. doi:10.1016/j.febslet.2004.07.002. PMID 15280039.
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