SpoIVB peptidase

Identifiers

Databases

PDB structures

SpoIVB peptidase (EC 3.4.21.116, sporulation factor IV B protease) is an enzyme.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB

This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.

References

↑ Wakeley, P.R.; Dorazi, R.; Hoa, N.T.; Bowyer, J.R.; Cutting, S.M. (2000). "Proteolysis of SpolVB is a critical determinant in signalling of pro-σ^K processing in Bacillus subtilis". Mol. Microbiol. 36: 1336–1348. doi:10.1046/j.1365-2958.2000.01946.x. PMID 10931284.
↑ Hoa, N.T.; Brannigan, J.A.; Cutting, S.M. (2001). "The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions". J. Bacteriol. 183: 4364–4373. doi:10.1128/jb.183.14.4364-4373.2001. PMID 11418578.
↑ Hoa, N.T.; Brannigan, J.A.; Cutting, S.M. (2002). "The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases". J. Bacteriol. 184: 191–199. doi:10.1128/jb.184.1.191-199.2002. PMID 11741860.
↑ Dong, T.C.; Cutting, S.M. (2003). "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of pro-σ^K in Bacillus subtilis". Mol. Microbiol. 49: 1425–1434. doi:10.1046/j.1365-2958.2003.03651.x. PMID 12940997.

SpoIVB peptidase at the US National Library of Medicine Medical Subject Headings (MeSH)

Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)

Digestive enzymes	Enteropeptidase Trypsin Chymotrypsin Elastase Neutrophil Pancreatic

Coagulation	factors: Thrombin Factor VIIa Factor IXa Factor Xa Factor XIa Factor XIIa Kallikrein PSA KLK1 KLK2 KLK3 KLK4 KLK5 KLK6 KLK7 KLK8 KLK9 KLK10 KLK11 KLK12 KLK13 KLK14 KLK15 fibrinolysis: Plasmin Plasminogen activator Tissue plasminogen activator Urinary plasminogen activator

Complement system	Factor B Factor D Factor I MASP MASP1 MASP2 C3-convertase

Other immune system	Chymase Granzyme Tryptase Proteinase 3/Myeloblastin

Venombin	Ancrod Batroxobin

Other	Acrosin Prolyl endopeptidase Pronase Proprotein convertases 1 2 Prostasin Reelin Subtilisin/Furin Streptokinase S1P Cathepsin A G

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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