Scytalidopepsin A

Scytalidopepsin A
Identifiers
EC number 3.4.23.31
CAS number 42613-34-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Scytalidopepsin A (EC 3.4.23.31, Scytalidium aspartic proteinase A, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum aspartic proteinase A-2, Scytalidium lignicolum aspartic proteinase A-I, Scytalidium lignicolum aspartic proteinase C, Scytalidium lignicolum carboxyl proteinase, Scytalidium lignicolum acid proteinase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO3H)7-Gly and Leu17-Val in the B chain of insulin

This enzyme is isolated from the fungus Scytalidium lignicolum.

References

  1. Oda, K.; Murao, S. (1974). "Purification and some enzymatic properties of acid protease A and B of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 38: 2435–2444. doi:10.1271/bbb1961.38.2435.
  2. Oda, K.; Murao, S. (1976). "Action of Scytalidium lignicolum acid proteases on insulin B-chain". Agric. Biol. Chem. 40: 1221–1225. doi:10.1271/bbb1961.40.1221.
  3. Oda, K.; Torishima, H.; Murao, S. (1986). "Purification and characterization of acid proteinase C of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 50: 651–658. doi:10.1271/bbb1961.50.651.
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