Pyrethroid hydrolase
| Pyrethroid hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.1.88 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Pyrethroid hydrolase (EC 3.1.1.88, pyrethroid-hydrolyzing carboxylesterase, pyrethroid-hydrolysing esterase, pyrethroid-hydrolyzing esterase, pyrethroid-selective esterase, pyrethroid-cleaving enzyme, permethrinase, PytH, EstP) is an enzyme with systematic name pyrethroid-ester hydrolase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- trans-permethrin + H2O (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
The enzyme is involved in degradation of pyrethroid pesticides.
References
- ↑ Wang, B.Z.; Guo, P.; Hang, B.J.; Li, L.; He, J.; Li, S.P. (2009). "Cloning of a novel pyrethroid-hydrolyzing carboxylesterase gene from Sphingobium sp. strain JZ-1 and characterization of the gene product". Appl. Environ. Microbiol. 75: 5496–5500. doi:10.1128/aem.01298-09. PMID 19581484.
- ↑ Wu, P.C.; Liu, Y.H.; Wang, Z.Y.; Zhang, X.Y.; Li, H.; Liang, W.Q.; Luo, N.; Hu, J.M.; Lu, J.Q.; Luan, T.G.; Cao, L.X. (2006). "Molecular cloning, purification, and biochemical characterization of a novel pyrethroid-hydrolyzing esterase from Klebsiella sp. strain ZD112". J. Agric. Food Chem. 54: 836–842. doi:10.1021/jf052691u. PMID 16448191.
- ↑ Liang, W.Q.; Wang, Z.Y.; Li, H.; Wu, P.C.; Hu, J.M.; Luo, N.; Cao, L.X.; Liu, Y.H. (2005). "Purification and characterization of a novel pyrethroid hydrolase from Aspergillus niger ZD11". J. Agric. Food Chem. 53: 7415–7420. doi:10.1021/jf051460k. PMID 16159167.
- ↑ Stok, J.E.; Huang, H.; Jones, P.D.; Wheelock, C.E.; Morisseau, C.; Hammock, B.D. (2004). "Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes". J. Biol. Chem. 279: 29863–29869. doi:10.1074/jbc.m403673200. PMID 15123619.
- ↑ Maloney, S.E.; Maule, A.; Smith, A.R. (1993). "Purification and preliminary characterization of permethrinase from a pyrethroid-transforming strain of Bacillus cereus". Appl. Environ. Microbiol. 59: 2007–2013. PMID 8357241.
- ↑ Guo, P.; Wang, B.; Hang, B.; Li, L.; Ali, W.; He, J.; Li, S. (2009). "Pyrethroid-degrading Sphingobium sp. JZ-2 and the purification and characterization of a novel pyrethroid hydrolase". Int. Biodeter. Biodegrad. 63: 1107–1112. doi:10.1016/j.ibiod.2009.09.008.
External links
- Pyrethroid hydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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