Protein-glucosylgalactosylhydroxylysine glucosidase
protein-glucosylgalactosylhydroxylysine glucosidase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 3.2.1.107 | ||||||||
CAS number | 72829-45-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
|
In enzymology, a protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) is an enzyme that catalyzes the chemical reaction
- protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine + H2O D-glucose + protein beta-D-galactosyl-L-hydroxylysine
Thus, the two substrates of this enzyme are protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine and H2O, whereas its two products are D-glucose and protein beta-D-galactosyl-L-hydroxylysine.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase. Other names in common use include 2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-, and lysine glucohydrolase.
References
- Hamazaki H, Hotta K (1979). "Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen". J. Biol. Chem. 254 (19): 9682–7. PMID 385589.
- Hamazaki H, Hotta K (1980). "Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens". Eur. J. Biochem. 111 (2): 587–91. doi:10.1111/j.1432-1033.1980.tb04975.x. PMID 7460918.
- Sternberg M, Spiro RG (1979). "Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity". J. Biol. Chem. 254 (20): 10329–36. PMID 385599.
This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.