Phorbol-diester hydrolase

phorbol-diester hydrolase
Identifiers
EC number 3.1.1.51
CAS number 81181-74-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a phorbol-diester hydrolase (EC 3.1.1.51) is an enzyme that catalyzes the chemical reaction

phorbol 12,13-dibutanoate + H2O phorbol 13-butanoate + butanoate

Thus, the two substrates of this enzyme are phorbol 12,13-dibutanoate and H2O, whereas its two products are phorbol 13-butanoate and butanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 12,13-diacylphorbate 12-acylhydrolase. Other names in common use include diacylphorbate 12-hydrolase, diacylphorbate 12-hydrolase, phorbol-12,13-diester 12-ester hydrolase, and PDEH.

References

    This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.