Peroxyureidoacrylate/ureidoacrylate amidohydrolase
| Peroxyureidoacrylate/ureidoacrylate amidohydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.5.1.110 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Peroxyureidoacrylate/ureidoacrylate amidohydrolase (EC 3.5.1.110, RutB) is an enzyme with systematic name (Z)-3-ureidoacrylate peracid amidohydrolase.[1] This enzyme catalyses the following chemical reaction
- (1) (Z)-3-ureidoacrylate peracid + H2O (Z)-3-peroxyaminoacrylate + CO2 + NH3 (overall reaction)
- (1a) (Z)-3-ureidoacrylate peracid + H2O (Z)-3-peroxyaminoacrylate + carbamate
- (1b) carbamate CO2 + NH3 (spontaneous)
- (2) (Z)-2-methylureidoacrylate peracid + H2O (Z)-2-methylperoxyaminoacrylate + CO2 + NH3 (overall reaction)
- (2a) (Z)-2-methylureidoacrylate peracid + H2O (Z)-2-methylperoxyaminoacrylate + carbamate
- (2b) carbamate CO2 + NH3 (spontaneous)
The enzyme also shows activity towards ureidoacrylate.
References
- ↑ Kim, K.S.; Pelton, J.G.; Inwood, W.B.; Andersen, U.; Kustu, S.; Wemmer, D.E. (2010). "The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems". J. Bacteriol. 192: 4089–4102. doi:10.1128/JB.00201-10. PMC 2916427
. PMID 20400551.
External links
- Peroxyureidoacrylate/ureidoacrylate amidohydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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