Peptidoglycolipid addressing protein

The Peptidoglycolipid Addressing Protein (GAP) Family[1] is a member of the Lysine Exporter (LysE) Superfamily.[2] It is listed as item 2.A.116 in the Transporter Classification Database.The mechanism of its action is not known, but this family has been shown to be a member of the LsyE superfamily. Therefore, these proteins are most likely secondary carriers.

The proposed generalized reaction catalyzed by members of the GAP family is:

PGL (in) → PGL (outer membrane).[3]

See also

References

  1. Sondén, Berit; Kocíncová, Dana; Deshayes, Caroline; Euphrasie, Daniel; Rhayat, Lamya; Laval, Françoise; Frehel, Claude; Daffé, Mamadou; Etienne, Gilles (2005-10-01). "Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface". Molecular Microbiology. 58 (2): 426–440. doi:10.1111/j.1365-2958.2005.04847.x. ISSN 0950-382X. PMID 16194230.
  2. Tsu, Brian V.; Saier, Milton H. (2015-01-01). "The LysE Superfamily of Transport Proteins Involved in Cell Physiology and Pathogenesis". PloS One. 10 (10): e0137184. doi:10.1371/journal.pone.0137184. ISSN 1932-6203. PMC 4608589Freely accessible. PMID 26474485.
  3. 2.A.116 The Peptidoglycolipid Addressing Protein (GAP) Family. Transporter Classification Database.

Further reading


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