Oviductin

Oviductin
Identifiers
EC number 3.4.21.120
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Oviductin (EC 3.4.21.120, oviductal protease) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Preferential cleavage at Gly-Ser-Arg373- of glycoprotein gp43 in Xenopus laevis coelemic egg envelope to yield gp41

This enzyme is also found in the Japanese toad (Bufo japonicus).

References

  1. Hardy, D.M.; Hedrick, J.L. (1992). "Oviductin. Purification and properties of the oviductal protease that processes the molecular weight 43,000 glycoprotein of the Xenopus laevis egg envelope". Biochemistry. 31: 4466–4472. doi:10.1021/bi00133a012. PMID 1581303.
  2. Lindsay, L.L.; Wieduwilt, M.J.; Hedrick, J.L. (1999). "Oviductin, the Xenopus laevis oviductal protease that processes egg envelope glycoprotein gp43, increases sperm binding to envelopes, and is translated as part of an unusual mosaic protein composed of two protease and several CUB domains". Biol. Reprod. 60: 989–995. doi:10.1095/biolreprod60.4.989. PMID 10084976.
  3. Hiyoshi, M.; Takamune, K.; Mita, K.; Kubo, H.; Sugimoto, Y.; Katagiri, C. (2002). "Oviductin, the oviductal protease that mediates gamete interaction by affecting the vitelline coat in Bufo japonicus: its molecular cloning and analyses of expression and posttranslational activation". Dev. Biol. 243: 176–184. doi:10.1006/dbio.2001.0558. PMID 11846486.
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