Mitochondrial protein-transporting ATPase
| mitochondrial protein-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.51 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a mitochondrial protein-transporting ATPase (EC 3.6.3.51) is an enzyme that catalyzes the chemical reaction
- ATP + H2O ADP + phosphate
Thus, the two substrates of this enzyme are ATP and H2O, whereas its two products are ADP and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (mitochondrial protein-importing).
References
- Rassow J; Meijer, M; Maarse, AC; Hönlinger, A; Dekker, PJ; Pfanner, N; Rassow, J (1997). "Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane". EMBO J. 16 (9): 2205–16. doi:10.1093/emboj/16.9.2205. PMC 1169823
. PMID 9171336. - Brunner M; Bauer, MF; Schneider, HC; Klaus, C; Dietmeier, K; Neupert, W; Brunner, M (1995). "The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system". Cell. 81 (7): 1085–93. doi:10.1016/S0092-8674(05)80013-3. PMID 7600576.
- Voos W, Martin H, Krimmer T, Pfanner N (1999). "Mechanisms of protein translocation into mitochondria". Biochim. Biophys. Acta. 1422 (3): 235–54. doi:10.1016/s0304-4157(99)00007-6. PMID 10548718.
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