Gamma-Renin

Gamma-renin
Identifiers
EC number 3.4.21.54
CAS number 85270-20-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Gamma-renin (EC 3.4.21.54) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen

This enzyme is present in submandibular glands of male mice.

References

  1. Poe, M.; Wu, J.K.; Florance, J.R.; Rodkey, J.A.; Bennett, C.D.; Hoogsteen, K. (1983). "Purification and properties of renin and γ-renin from the mouse submaxillary gland". J. Biol. Chem. 258: 2209–2216. PMID 6337154.
  2. Drinkwater, C.C.; Evans, B.A.; Richards, R.I. (1988). "Sequence and expression of mouse γ-renin". J. Biol. Chem. 263: 8565–8568. PMID 3288617.
This article is issued from Wikipedia - version of the 5/19/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.