Flusilazole

Flusilazole
Names


IUPAC name 1-((bis(4-fluorophenyl)methylsilyl)methyl)-1H-1,2,4-triazole
Other names DPX-H6573;
Identifiers
CAS Number	85509-19-9^Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:81922^N
ChemSpider	66326^N
ECHA InfoCard	100.107.525
PubChem	73675
InChI InChI=1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3^N Key: FQKUGOMFVDPBIZ-UHFFFAOYSA-N^N InChI=1/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3 Key: FQKUGOMFVDPBIZ-UHFFFAOYAI
SMILES c2ncnn2C[Si](C)(c(cc1)ccc1F)c3ccc(F)cc3
Properties
Chemical formula	C₁₆H₁₅F₂N₃Si
Density	315.392 g/cm³
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Flusilazole (DPX-H6573) is an organosilicon fungicide invented by DuPont, which is used to control fungal infections on a variety of fruit and vegetable crops.^[1]^[2]^[3] It is moderately toxic to animals and has been shown to produce birth defects and embryotoxicity at high doses.^[4]^[5]

External links

Flusilazole in the Pesticide Properties DataBase (PPDB)

References

↑ Moberg, W. K.; Basarab, G. S.; Cuomo, J.; Liang, P. H. (1987). "Biologically Active Organosilicon Compounds". 355: 288. doi:10.1021/bk-1987-0355.ch026.
↑ Bostanian NJ, Larocque N, Chouinard G, Coderre D (November 2001). "Baseline toxicity of several pesticides to Hyaliodes vitripennis (Say) (Hemiptera: Miridae)". Pest Management Science. 57 (11): 1007–10. doi:10.1002/ps.374. PMID 11721516.
↑ Eckert MR, Rossall S, Selley A, Fitt BD (April 2010). "Effects of fungicides on in vitro spore germination and mycelial growth of the phytopathogens Leptosphaeria maculans and L. biglobosa (phoma stem canker of oilseed rape)". Pest Management Science. 66 (4): 396–405. doi:10.1002/ps.1890. PMID 20013877.
↑ Farag AT, Ibrahim HH (February 2007). "Developmental toxic effects of antifungal flusilazole administered by gavage to mice". Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 80 (1): 12–7. doi:10.1002/bdrb.20098. PMID 17187383.
↑ Hermsen SA, van den Brandhof EJ, van der Ven LT, Piersma AH (January 2011). "Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies". Toxicology in Vitro. 25 (3): 745–753. doi:10.1016/j.tiv.2011.01.005. PMID 21238576.

This article is issued from Wikipedia - version of the 7/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.