Florantyrone

Florantyrone
Clinical data

ATC code	none
Identifiers
IUPAC name 4-fluoranthen-8-yl-4-oxobutanoic acid
CAS Number	519-95-9^Y
PubChem (CID)	10617
DrugBank	DB08975^N
ChemSpider	10172^N
UNII	UZ5LMI200P^Y
ChEMBL	CHEMBL2106357^N
ECHA InfoCard	100.007.528
Chemical and physical data
Formula	C₂₀H₁₄O₃
Molar mass	302.323 g/mol
3D model (Jmol)	Interactive image
Melting point	195 °C (383 °F)
Solubility in water	soluble in methanol, ethanol, sodium carbonate mg/mL (20 °C)
SMILES C1=CC2=C3C(=C1)C4=C(C3=CC=C2)C=C(C=C4)C(=O)CCC(=O)O
InChI InChI=1S/C20H14O3/c21-18(9-10-19(22)23)13-7-8-14-15-5-1-3-12-4-2-6-16(20(12)15)17(14)11-13/h1-8,11H,9-10H2,(H,22,23)^N Key:QOBAOSCOLAGPKI-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Florantyrone (INN; also known as Fluorantyrone) is a drug used in the treatment of biliary dyskinesia. It is also known as a cholagogue and choleretic.^[1]

It is manufactured from fluoranthene and succinic anhydride in the presence of aluminum chloride in a nitrobenzene solution. (US PATENT 2,560,425 (1951 To Miles Lab)).

It is chemical related to fenbufen.

References

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