Farnesyl diphosphatase

Farnesyl diphosphatase
Identifiers
EC number 3.1.7.6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase.[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O (2E,6E)-farnesol + diphosphate

The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids.

References

  1. Song, L. (2006). "A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol". Appl. Biochem. Biotechnol. 128: 149–158. doi:10.1385/abab:128:2:149. PMID 16484724.
  2. Tsai, S.-C.; Gaylor, J.L. (1966). "Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase". J. Biol. Chem. 241: 4043–4050. PMID 4288361.
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