FUCA2

FUCA2

Identifiers

FUCA2, dJ20N2.5, fucosidase, alpha-L- 2, plasma

External IDs

MGI: 1914098 HomoloGene: 119 GeneCards: FUCA2

Gene ontology
Molecular function	• protein binding • hydrolase activity • alpha-L-fucosidase activity • hydrolase activity, acting on glycosyl bonds
Cellular component	• extracellular space • extracellular region • extracellular exosome
Biological process	• fucose metabolic process • metabolic process • regulation of entry of bacterium into host cell • response to bacterium • glycoside catabolic process • carbohydrate metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


2519


66848


ENSG00000001036


ENSMUSG00000019810


Q9BTY2 Q7Z6V2


Q99KR8

RefSeq (mRNA)


NM_032020


NM_025799

RefSeq (protein)


NP_114409.2


NP_080075.2

Location (UCSC)

Chr 6: 143.49 – 143.51 Mb

Chr 10: 13.5 – 13.52 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Plasma alpha-L-fucosidase (see alpha-L-fucosidase) is an enzyme that in humans is encoded by the FUCA2 gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Eiberg H, Mohr J, Nielsen LS (Oct 1984). "Linkage of plasma alpha-L-fucosidase (FUCA2) and the plasminogen (PLG) system". Clin Genet. 26 (1): 23–9. doi:10.1111/j.1399-0004.1984.tb00782.x. PMID 6590153.
↑ "Entrez Gene: FUCA2 fucosidase, alpha-L- 2, plasma".

Further reading

Narahara K, Tsuji K, Yokoyama Y, et al. (1991). "Specification of small distal 6q deletions in two patients by gene dosage and in situ hybridization study of plasminogen and alpha-L-fucosidase 2.". Am. J. Med. Genet. 40 (3): 348–53. doi:10.1002/ajmg.1320400322. PMID 1951444.
O'Brien JS, Willems PJ, Fukushima H, et al. (1988). "Molecular biology of the alpha-L-fucosidase gene and fucosidosis.". Enzyme. 38 (1-4): 45–53. PMID 2894306.
Cordero OJ, Merino A, Páez de la Cadena M, et al. (2001). "Cell surface human alpha-L-fucosidase.". Eur. J. Biochem. 268 (11): 3321–31. doi:10.1046/j.1432-1327.2001.02237.x. PMID 11389735.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

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