FCRL2

FCRL2

Identifiers

FCRL2, CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C, Fc receptor like 2

External IDs

HomoloGene: 57121 GeneCards: FCRL2

Gene ontology
Molecular function	• protein binding • SH3/SH2 adaptor activity
Cellular component	• plasma membrane • membrane • integral component of membrane
Biological process	• cell-cell signaling • positive regulation of signal transduction
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


79368


n/a


ENSG00000132704


n/a


Q96LA5


n/a

RefSeq (mRNA)


NM_001159488 NM_030764 NM_138738


n/a

RefSeq (protein)


NP_001152960.1 NP_110391.2


n/a

Location (UCSC)

Chr 1: 157.75 – 157.78 Mb

n/a

PubMed search

^[1]

n/a

View/Edit Human

Fc receptor-like protein 2 is a protein that in humans is encoded by the FCRL2 gene.^[2]^[3]

References

↑ "Human PubMed Reference:".
↑ Xu MJ, Zhao R, Zhao ZJ (Feb 2001). "Molecular cloning and characterization of SPAP1, an inhibitory receptor". Biochem Biophys Res Commun. 280 (3): 768–75. doi:10.1006/bbrc.2000.4213. PMID 11162587.
↑ "Entrez Gene: FCRL2 Fc receptor-like 2".

Further reading

Davis RS, Wang YH, Kubagawa H, Cooper MD (2001). "Identification of a family of Fc receptor homologs with preferential B cell expression.". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772–7. doi:10.1073/pnas.171308498. PMC 55528. PMID 11493702.
Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.". Blood. 99 (8): 2662–9. doi:10.1182/blood.V99.8.2662. PMID 11929751.
Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1.". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL.". Immunogenetics. 59 (4): 323–8. doi:10.1007/s00251-007-0195-9. PMID 17273841.

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