Exodeoxyribonuclease III
| Exodeoxyribonuclease III | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.11.2 | ||||||||
| CAS number | 9037-44-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Exodeoxyribonuclease III (EC 3.1.11.2, Escherichia coli exonuclease III, E. coli exonuclease III, endoribonuclease III) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
This enzyme has a preference for double-stranded DNA.
References
- ↑ Lindahl, T.; Gally, J.A.; Edelman, G.M. (1969). "Properties of deoxyribonuclease 3 from mammalian tissues". J. Biol. Chem. 244: 5014–5019. PMID 5824576.
- ↑ Richardson, C.C.; Kornberg, A. (1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification of the enzyme and characterization of the phosphatase activity". J. Biol. Chem. 239: 242–250. PMID 14114850.
- ↑ Richardson, C.C.; Lehman, I.R.; Kornberg, A. (1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II. Characterization of the exonuclease activity". J. Biol. Chem. 239: 251–258. PMID 14114851.
External links
- Exodeoxyribonuclease III at the US National Library of Medicine Medical Subject Headings (MeSH)
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