Exodeoxyribonuclease (phage SP3-induced)

Exodeoxyribonuclease (phage SP3-induced)
Identifiers
EC number 3.1.11.4
CAS number 37288-30-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Exodeoxyribonuclease (phage SP3-induced) (EC 3.1.11.4, phage SP3 DNase, DNA 5'-dinucleotidohydrolase, deoxyribonucleate 5'-dinucleotidase, deoxyribonucleic 5'-dinucleotidohydrolase, bacteriophage SP3 deoxyribonuclease) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates

Preference for single-stranded DNA.

References

  1. Trilling, D.M.; Aposhian, H.V. (1968). "Sequential cleavage of dinucleotides from DNA by phage Sp3 DNAse". Proc. Natl. Acad. Sci. USA. 60 (1): 214–221. Bibcode:1968PNAS...60..214T. doi:10.1073/pnas.60.1.214. PMC 539104Freely accessible. PMID 4968633.
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