CDP-paratose 2-epimerase
CDP-abequose epimerase | |||||||||
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Identifiers | |||||||||
EC number | 5.1.3.10 | ||||||||
CAS number | 37318-36-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a CDP-paratose 2-epimerase (EC 5.1.3.10) is an enzyme that catalyzes the chemical reaction
- CDP-3,6-dideoxy-D-glucose CDP-3,6-dideoxy-D-mannose
Hence, this enzyme has one substrate, CDP-3,6-dideoxy-D-glucose, and one product, CDP-3,6-dideoxy-D-mannose.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is CDP-3,6-dideoxy-D-glucose 2-epimerase. Other names in common use include CDP-paratose epimerase, cytidine diphosphoabequose epimerase, cytidine diphosphodideoxyglucose epimerase, cytidine diphosphoparatose epimerase, and cytidine diphosphate paratose-2-epimerase. It is also incorrectly known as CDP-abequose epimerase, and CDP-D-abequose 2-epimerase. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.
References
- Matsuhashi S (1966). "Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II Reversible 2-epimerization of cytidine diphosphate paratose". J. Biol. Chem. 241 (18): 4275–82. PMID 5924649.
- Liu HW, Thorson JS (1994). "Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria". Annu. Rev. Microbiol. 48: 223–56. doi:10.1146/annurev.mi.48.100194.001255. PMID 7826006.