Blood group B linear chain alpha-1,3-galactosidase
| Baicalin-beta-D-glucuronidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.167 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Baicalin-beta-D-glucuronidase (EC 3.2.1.167, baicalinase) is an enzyme with systematic name 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- baicalin + H2O baicalein + D-glucuronate
The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.
References
- ↑ Ikegami, F.; Matsunae, K.; Hisamitsu, M.; Kurihara, T.; Yamamoto, T.; Murakoshi, I. (1995). "Purification and properties of a plant β-D-glucuronidase form Scutellaria root". Biol. Pharm. Bull. 18: 1531–1534. doi:10.1248/bpb.18.1531. PMID 8593473.
- ↑ Zhang, C.; Zhang, Y.; Chen, J.; Liang, X. (2005). "Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge". Proc. Biochem. 40: 1911–1915. doi:10.1016/j.procbio.2004.07.003.
- ↑ Sasaki, K.; Taura, F.; Shoyama, Y.; Morimoto, S. (2000). "Molecular characterization of a novel β-glucuronidase from Scutellaria baicalensis Georgi". J. Biol. Chem. 275: 27466–27472. doi:10.1074/jbc.m004674200. PMID 10858442.
- ↑ Morimoto, S.; Harioka, T.; Shoyama, Y. (1995). "Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi". Planta. 195: 535–540. doi:10.1007/bf00195712.
External links
- Baicalin-beta-D-glucuronidase at the US National Library of Medicine Medical Subject Headings (MeSH)
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