Blood-group-substance endo-1,4-beta-galactosidase

Blood-group-substance endo-1,4-beta-galactosidase
Identifiers
EC number 3.2.1.102
CAS number 52720-51-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Blood-group-substance endo-1,4-beta-galactosidase (EC 3.2.1.102, endo-beta-galactosidase, blood-group-substance 1,4-beta-D-galactanohydrolase) is an enzyme with systematic name blood-group-substance 4-beta-D-galactanohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction

Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances

Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to a 1,3-alpha-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-alpha-D-fucosyl residue.

References

  1. Fukuda, M.N.; Matsumara, G. (1976). "Endo-β-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein". J. Biol. Chem. 251: 6218–6225. PMID 135762.
  2. Nakazawa, K.; Suzuki, S. (1975). "Purification of keratan sulfate-endogalactosidase and its action on keratan sulfates of different origin". J. Biol. Chem. 250: 912–917. PMID 234443.
  3. Takasaki, S.; Kobata, A. (1976). "Purification and characterization of an endo-β-galactosidase produced by Diplococcus pneumoniae". J. Biol. Chem. 251: 3603–3609. PMID 6459.

External links

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