Beta-phellandrene synthase (neryl-diphosphate-cyclizing)

Beta-phellandrene synthase (neryl-diphosphate-cyclizing)
Identifiers
EC number 4.2.3.51
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-phellandrene synthase (neryl-diphosphate-cyclizing) (EC 4.2.3.51, phellandrene synthase 1, PHS1, monoterpene synthase PHS1) is an enzyme with systematic name neryl-diphosphate diphosphate-lyase (cyclizing; beta-phellandrene-forming).[1] This enzyme catalyses the following chemical reaction

neryl diphosphate beta-phellandrene + diphosphate

The enzyme from Solanum lycopersicum has very poor affinity with geranyl diphosphate.

References

  1. Schilmiller, A.L.; Schauvinhold, I.; Larson, M.; Xu, R.; Charbonneau, A.L.; Schmidt, A.; Wilkerson, C.; Last, R.L.; Pichersky, E. (2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate". Proc. Natl. Acad. Sci. USA. 106: 10865–10870. doi:10.1073/pnas.0904113106. PMID 19487664.

External links

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