Beta-farnesene synthase

Beta-farnesene synthase
Identifiers
EC number 4.2.3.47
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-farnesene synthase (EC 4.2.3.47, farnesene synthase, terpene synthase 10, terpene synthase 10-B73, TPS10) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-beta-farnesene-forming).[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (E)-beta-farnesene + diphosphate

References

  1. Zhao, B.; Lei, L.; Vassylyev, D.G.; Lin, X.; Cane, D.E.; Kelly, S.L.; Yuan, H.; Lamb, D.C.; Waterman, M.R. (2009). "Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site". J. Biol. Chem. 284: 36711–36719. doi:10.1074/jbc.M109.064683. PMC 2794785Freely accessible. PMID 19858213.
  2. Picaud, S.; Brodelius, M.; Brodelius, P.E. (2005). "Expression, purification and characterization of recombinant (E)-β-farnesene synthase from Artemisia annua". Phytochemistry. 66 (9): 961–967. doi:10.1016/j.phytochem.2005.03.027. PMID 15896363.
  3. Kollner, T.G.; Gershenzon, J.; Degenhardt, J. (2009). "Molecular and biochemical evolution of maize terpene synthase 10, an enzyme of indirect defense". Phytochemistry. 70 (9): 1139–1145. doi:10.1016/j.phytochem.2009.06.011. PMID 19646721.
  4. Schnee, C.; Kollner, T.G.; Held, M.; Turlings, T.C.; Gershenzon, J.; Degenhardt, J. (2006). "The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores". Proc. Natl. Acad. Sci. USA. 103 (4): 1129–1134. doi:10.1073/pnas.0508027103. PMID 16418295.
  5. Maruyama, T.; Ito, M.; Honda, G. (2001). "Molecular cloning, functional expression and characterization of (E)-β farnesene synthase from Citrus junos". Biol. Pharm. Bull. 24 (10): 1171–1175. doi:10.1248/bpb.24.1171. PMID 11642326.
  6. Crock, J.; Wildung, M.; Croteau, R. (1997). "Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha × piperita, L.) that produces the aphid alarm pheromone (E)-β-farnesene". Proc. Natl. Acad. Sci. USA. 94 (24): 12833–12838. doi:10.1073/pnas.94.24.12833. PMID 9371761.
  7. Schnee, C.; Kollner, T.G.; Gershenzon, J.; Degenhardt, J. (2002). "The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-β-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage". Plant Physiol. 130 (4): 2049–2060. doi:10.1104/pp.008326. PMID 12481088.
  8. Huber, D.P.W.; Philippe, R.N.; Godard, K.-A.; Sturrock, R.N.; Bohlmann, J. (2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66 (12): 1427–1439. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711.

External links

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