Anhydrosialidase
Anhydrosialidase | |||||||||
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Identifiers | |||||||||
EC number | 4.2.2.15 | ||||||||
CAS number | 157857-11-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, an anhydrosialidase (EC 4.2.2.15) is an enzyme that catalyzes the chemical reaction
- Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is glycoconjugate sialyl-lyase (2,7-cyclizing). Other names in common use include anhydroneuraminidase, sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing), and sialidase L.
References
- Li YT, Nakagawa H, Ross SA, Hansson GC, Li SC (1990). "A novel sialidase which releases 2,7-anhydro-alpha-N-acetylneuraminic acid from sialoglycoconjugates". J. Biol. Chem. 265 (35): 21629–33. PMID 2254319.
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