Ameltolide
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| Clinical data | |
|---|---|
| ATC code | None |
| Identifiers | |
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| CAS Number | 787-93-9 |
| PubChem (CID) | 13086 |
| ChemSpider | 12541 |
| Chemical and physical data | |
| Formula | C15H16N2O |
| Molar mass | 240.300 g/mol |
| 3D model (Jmol) | Interactive image |
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Ameltolide, a 4-aminobenzamide derivative, is an experimental anticonvulsant agent, effective at inhibiting seizures in animal models.[1] It is non-toxic at dosing levels and no undesirable side effects are attributable to its application.[2]
References
- ↑ Robertson, David W.; Beedle, E. E.; Krushinski, Joseph H.; Lawson, Ronald R.; Parli, C. John; Potts, Brian; Leander, J. David (1991). "Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant". Journal of Medicinal Chemistry. 34 (4): 1253–7. doi:10.1021/jm00108a003. PMID 2016702.
- ↑ Higdon, Gary L.; McKinley, Edmund R.; Markham, Janet K. (1991). "Ameltolide. I: Developmental toxicology studies of a novel anticonvulsant". Teratology. 44 (1): 37–44. doi:10.1002/tera.1420440107. PMID 1957261.
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