Alpha-amino-acid esterase

alpha-amino-acid esterase
Identifiers
EC number 3.1.1.43
CAS number 74506-40-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an alpha-amino-acid esterase (EC 3.1.1.43) is an enzyme that catalyzes the chemical reaction

an alpha-amino acid ester + H2O an alpha-amino acid + an alcohol

Thus, the two substrates of this enzyme are alpha-amino acid ester and H2O, whereas its two products are alpha-amino acid and alcohol.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is alpha-amino-acid-ester aminoacylhydrolase. This enzyme is also called alpha-amino acid ester hydrolase.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1MPX, 1NX9, 1RYY, 2B4K, and 2B9V.

References


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