3-hydroxypropionyl-CoA synthase

3-hydroxypropionyl-CoA synthase
Identifiers
EC number 6.2.1.36
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-hydroxypropionyl-CoA synthase (EC 6.2.1.36, 3-hydroxypropionyl-CoA synthetase (AMP-forming), 3-hydroxypropionate-CoA ligase) is an enzyme with systematic name hydroxypropionate:CoA ligase (AMP-forming).[1][2] This enzyme catalyses the following chemical reaction

3-hydroxypropionate + ATP + CoA 3-hydroxypropionyl-CoA + AMP + diphosphate

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.

References

  1. Berg, I.A.; Kockelkorn, D.; Buckel, W.; Fuchs, G. (2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318: 1782–1786. doi:10.1126/science.1149976. PMID 18079405.
  2. Alber, B.E.; Kung, J.W.; Fuchs, G. (2008). "3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation". J. Bacteriol. 190 (4): 1383–1389. doi:10.1128/JB.01593-07. PMID 18165310.

External links

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