3-deoxyoctulosonase
| 3-deoxyoctulosonase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.144 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a 3-deoxyoctulosonase (EC 3.2.1.144) is an enzyme that catalyzes the chemical reaction
- 3-deoxyoctulosonyl-lipopolysaccharide + H2O 3-deoxyoctulosonic acid + lipopolysaccharide
Thus, the two substrates of this enzyme are 3-deoxyoctulosonyl-lipopolysaccharide and H2O, whereas its two products are 3-deoxyoctulosonic acid and lipopolysaccharide.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 3-deoxyoctulosonyl-lipopolysaccharide hydrolase. This enzyme is also called alpha-Kdo-ase.
References
- Li YT, Wang LX, Pavlova NV, Li SC, Lee YC (October 1997). "alpha-KDOase activity in oyster and synthesis of alpha- and beta-4-methylumbelliferyl ketosides of 3-deoxy-D-manno-octulosonic acid". The Journal of Biological Chemistry. 272 (42): 26419–24. doi:10.1074/jbc.272.42.26419. PMID 9334217.
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