2'-hydroxybiphenyl-2-sulfinate desulfinase

2-(2-hydroxyphenyl)benzenesulfinate hydrolase
Identifiers
EC number 3.13.1.3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 2'-hydroxybiphenyl-2-sulfinate desulfinase (EC 3.13.1.3) is an enzyme that catalyzes the chemical reaction

2'-hydroxybiphenyl-2-sulfinate + H2O 2-hydroxybiphenyl + sulfite

Thus, the two substrates of this enzyme are 2'-hydroxybiphenyl-2-sulfinate and H2O, whereas its two products are 2-hydroxybiphenyl and sulfite.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-sulfur bonds. The systematic name of this enzyme class is 2'-hydroxybiphenyl-2-sulfinate sulfohydrolase. Other names in common use include gene dszB-encoded hydrolase, 2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase, DszB, HBPSi desulfinase, 2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase, HPBS desulfinase, 2-(2-hydroxyphenyl)benzenesulfinate hydrolase, 2-(2'-hydroxyphenyl)benzenesulfinate desulfinase, and 2-(2-hydroxyphenyl)benzenesulfinate desulfinase.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2DE2, 2DE3, and 2DE4.

References

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